James Harrison: Australian whose blood saved 2.4 million babies dies

Kelly Ng

BBC News

Essence of the Australian Red Cross James Harrison with his grandson, Trey, in an earlier pictureEssence of the Australian Red Cross

One of the most famous blood donors in the world, whose plasma saved more than 2 million children ‘ life, passed away.

James Harrison passed away on February 17 while he was sleeping in a nursing home in New South Wales, Australia, according to his home. He was 88.

Harrison’s blood, which is referred to as the “man with the beautiful arm,” contained a rare antibody called Anti-D, which is used to create medication for pregnant mothers whose blood is at risk of infecting their newborn children.

Harrison had been given a benefactor after having transplants while having a significant neck operation at the age of 14, according to the Australian Red Cross Blood Service, who paid gift to him.

He began giving heart serum when he was 18 and continued doing so until he was 81.

He held the title of “world record for most body blood donated” until 2022 when a US citizen overcame him in that year.

Tracey Mellowship, Harrison’s child, claimed that her papa was “very happy to have saved so many life, without any expense or pain.”

She continued,” He always said it doesn’t hurt, and the lifestyle you save may be your own.”

Additionally, Mellowship and two of Harrison’s children have been given anti-D vaccinations.

James was moved to learn about the numerous individuals like ours, which were a result of his kindness, she said.

Anti-D jabs protect unborn children from the lethal blood disorder known as the fetal and kid haemolytic disease, or HDFN.

The problem occurs during pregnancy when the mother’s red blood cells are incompatible with the baby’s growing red blood cells.

The family’s immune system then recognizes the hazard presented by the baby’s blood cells and makes antibodies to combat them. This can really hurt the infant, leading to severe heart failure, malnutrition, or even death.

Getty Images Harrison at his 537th blood donation in December 1992Getty Images

One in two children diagnosed with HDFN died before anti-D treatments were developed in the middle of the 1960s.

Harrison’s blood is thought to be so high in anti-D, but some reports claim it may have been caused by the large blood transfusion he received at age 14; it is not known how this drug came to be so high.

According to the Australian Red Cross Blood Service, also known as Lifeblood, there are less than 200 anti-D sponsors in Australia, but they donate an estimated 45, 000 mothers and their children annually.

By replicating heart and immune cells from Harrison and other sponsors, Lifeblood has been working with Australia’s Walter and Eliza Hall Institute of Medical Research to create anti-D antibodies in the facility.

Researchers who are involved hope that lab-made anti-D may one day be applied to the treatment of pregnant women around the world.

” Developing a new therapy has long been the “holy grail,” according to Lifeblood’s study director, David Irving.

He made note of the underrepresentation of donors who would like to make regular donations and who are able to develop antibodies in sufficient quantity and quality.